一名62岁的老人在初级中枢神经系统淋巴瘤后出现严重的白天嗜睡
Jindapa Srikajon1, Athiwat Tripipitsiriwat2, Jeremy E Orr3
1Siriraj Sleep Center, Faculty of Medicine Siriraj Hospital, Mahidol University, Thailand.
Chest
|February 11, 2026
概括
一名患有复发性中枢神经系统淋巴瘤的患者出现了睡眠呼吸障碍. 淋巴瘤的治疗导致了缓解,但睡眠呼吸暂停症状仍然存在,突出显示了潜在的长期并发症.
科学领域:
- 神经学 神经学
- 在瘤学瘤学.
- 睡眠医学 睡眠医学
背景情况:
- 中枢神经系统淋巴瘤 (CNSL) 是一种罕见且具有攻击性的恶性瘤.
- 复发的CNSL可以呈现出各种神经系统症状.
- 睡眠障碍在患有神经疾病的患者中很常见.
研究的目的:
- 报告一个患有复发性扩散性大B细胞淋巴瘤的患者睡眠呼吸障碍病例.
- 讨论CNSL治疗和随后的睡眠障碍之间的潜在联系.
- 突出评估患者睡眠症状的重要性有史以来的CNSL.
主要方法:
- 一个62岁的男性患有复发性初级CNSL的案例介绍.
- 诊断工作包括脑MRI和活检.
- 患者出现了打的症状,目击呼吸暂停和严重的白天嗜睡.
- 治疗包括高剂量甲状腺素,修复药和全脑放射治疗.
主要成果:
- 大脑活检证实复发的扩散性大B细胞淋巴瘤.
- 患者在治疗后实现了缓解.
- 尽管缓解,但患者继续出现显著的睡眠呼吸暂停症状.
- 评估了与睡眠呼吸暂停相关的神经检查和呼吸系统参数.
结论:
- 复发性CNSL及其治疗可能会导致睡眠呼吸障碍的发展.
- 持续的睡眠呼吸暂停症状要求进行彻底的调查,即使在成功治疗淋巴瘤后也是如此.
- 涉及神经学和睡眠医学的多学科管理对这些患者至关重要.
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