老年石骨髓炎的临床特征和结果:对333个文献报告病例的综合分析
Mahmoud Qalalwa1, Zi-Xian Liu2, Li-Li Qiu1
1Division of Orthopaedics and Traumatology, Department of Orthopaedics, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Geriatrics & gerontology international
|February 11, 2026
概括
老年骨髓炎 (GCO) 主要影响男性,通常源于糖尿病足部感染. 手术治疗是常见的,但复发率和截肢率仍然是一个重大挑战.
科学领域:
- 整形外科 整形外科 整形外科
- 传染性疾病 传染性疾病
- 足部医学是一门专业.
背景情况:
- 骨髓炎 (CO) 在骨科手术中存在独特的挑战,特别是在老年患者中.
- 由于解剖学和功能方面的考虑,老年骨髓炎 (GCO) 需要特殊的理解.
研究的目的:
- 综合审查老年骨髓炎的临床表现,治疗策略和结果.
- 分析关于GCO的现有文献,以告知临床实践和未来的研究.
主要方法:
- 在PubMed,Embase和Cochrane图书馆 (2000-2021) 的系统文献搜索.
- 包括60岁及以上的患者中对CO的英语研究.
- 使用NIH尺度和数据提取进行聚合分析的质量评估.
主要成果:
- 分析了59篇与333名患者的文章;中位数年龄62岁,中位数症状持续时间6.6个月.
- 糖尿病足部感染是主要原因 (216例),金黄色葡萄球菌是最常见的病原体.
- 手术干预率高 (97.6%),具有整体复发 (30.7%) 和四肢截肢 (28.7%) 的风险.
结论:
- GCO主要影响男性,糖尿病是主要的危险因素.
- 金黄色葡萄球菌是发现的最常见的病原体.
- 尽管手术率很高,但GCO与大量的复发和截肢率有关.
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