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Updated: Feb 13, 2026

Comprehensive DNA Methylation Analysis Using a Methyl-CpG-binding Domain Capture-based Method in Chronic Lymphocytic Leukemia Patients
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Published on: June 16, 2017

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DNMT3B1的染色体结合和N端域为发育调节的CpG岛甲基化赋予了特异性

Komal Yasmin1, Tatyana B Nesterova1, Neil Brockdorff2

  • 1Department of Biochemistry, University of Oxford, Oxford OX1 3QU, United Kingdom.

Genes & development
|February 11, 2026
PubMed
概括

DNA甲基转移酶 DNMT3A 和 DNMT3B 建立了 CpG 的甲基化. 在发育过程中,DNMT3B对CpG岛屿 (CGI) 显示出独特的特异性,这种作用是使用胚胎干细胞模型阐明的.

关键词:
在CpG岛上.通过DNA甲基化.在X无活化过程中,在这种情况下,染色染色素表观遗传学是指表观遗传学.

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