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Updated: Feb 13, 2026

Burn Injury-Induced Pain and Depression-Like Behavior in Mice
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佩拉曼奈尔治疗通过调节GluN2B表达来缓解小鼠的抑郁症行为,以改善激发性突触传输

Jin-Ming Liu1, Yan-Lin Zhang2, Fang Guo1

  • 1Key Laboratory of Mental Health of the Ministry of Education, Guangdong-Hong Kong-Macao Greater Bay Area Center for Brain Science and Brain-Inspired Intelligence, Guangdong-Hong Kong Joint Laboratory for Psychiatric Disorders, Guangdong Province Key Laboratory of Psychiatric Disorders, Guangdong Basic Research Center of Excellence for Integrated Traditional and Western Medicine for Qingzhi Diseases, Department of Neurobiology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, P.R. China.

Translational psychiatry
|February 11, 2026
PubMed
概括

类药物佩拉曼奈尔通过调节小鼠的谷氨酸受体,显示出快速的抗抑郁作用. 这一发现表明了潜在的新型抑郁症治疗方法,特别是在同时发生的患者中.

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