通过TAX1BP1指导的Golgiphagy对STING信号进行负反调节

Sujit Suklabaidya1, Suchitra Mohanty1,2, Irene E Reider1

  • 1Department of Cell and Biological Systems, Penn State College School of Medicine, Hershey, PA, USA.

Nature communications
|February 11, 2026
PubMed
概括

选择性自受体TAX1BP1通过促进STING降解来负面调节cGAS-STING通路. 缺少TAX1BP1会增加I型干扰素 (IFN) 的产生和炎症.

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