CSN5i-3是一种COP9信号体的奥托斯特分子抑制剂

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Updated: Feb 13, 2026

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Huigang Shi1, Xiaorong Wang2, Clinton Yu2

  • 1Department of Pharmacology, University of Washington, Seattle, WA, USA.

Nature
|February 11, 2026
PubMed
概括

整形抑制剂通过分子合剂机制,意外地获得了基质依赖的功效. 这种新的方法通过利用酶-基质相互作用来提高向COP9信号体 (CSN) 的抑制剂的有效性.

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