与脑膜瘤的内栓塞和料封闭相关的输液变化:一项动脉旋转标记研究
Masao Fukumura1, Hideki Kashiwagi2, Kohei Yoshimura2
1Department of Neurosurgery and Neuroendovascular Therapy, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, 569-8686, Japan. masao.fukumura@ompu.ac.jp.
在脑膜瘤患者中,内栓塞显著降低了瘤血流 (TBF),超过了料封闭. 动脉旋转标签 (ASL) 证实了这些输液变化,支持内栓塞作为更有效的策略.
科学领域:
- 神经辐射学神经辐射学
- 干预性放射学 干预性放射学
- 医疗成像医学成像
背景情况:
- 手术前栓塞是脑膜瘤手术的辅助疗法,但它的好处仍在争论中.
- 内栓塞可能比料封闭更有效地减少瘤血流 (TBF).
- 对比这些栓塞技术的客观输液数据是有限的.
研究的目的:
- 通过动脉旋转标记 (ASL) 来评估术前栓塞后脑膜瘤的输液变化.
- 为了比较内栓塞与料封闭在减少TBF的有效性.
主要方法:
- 对43名经历了手术前栓塞的脑膜瘤患者的回顾性分析.
- 动脉旋转标记 (ASL) 用于测量TBF和脑血流 (CBF) 在栓塞前和后.
- 患者被分为内栓塞和料封闭组. 计算了TBF/CBF (T/N) 的比率和流量减少率.
主要成果:
- 内栓塞显著降低了术后的T/N比率 (P=0.003).
- 料封闭显示T/N比率没有显著变化 (P=0.36).
- 与管封闭 (24.1%;P=0.001) 相比,内栓塞 (50.6%) 的流量减少率显著高于内栓塞 (24.1%;P=0.001).
结论:
- 与Feeder封闭相比,脑膜瘤瘤血流 (TBF) 的减少更大.
- ASL提供客观的基于 perfusion 的证据,支持内栓塞的有效性.
- 研究结果表明,内栓塞可能是治疗脑膜瘤的更有效的术前策略.
更多相关视频
09:11Embolic Middle Cerebral Artery Occlusion MCAO for Ischemic Stroke with Homologous Blood Clots in Rats
Published on: September 17, 2014
12:15Optimized System for Cerebral Perfusion Monitoring in the Rat Stroke Model of Intraluminal Middle Cerebral Artery Occlusion
Published on: February 17, 2013
相关概念视频
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
Pulmonary Embolism I: Introduction
NMR Spectroscopy: Spin–Spin Coupling
Spin–Spin Coupling: One-Bond Coupling
Spin–Spin Coupling Constant: Overview
Qualitatively, any spin plus-half nucleus polarizes the spins of its electrons to the minus-half state. Consequently, the paired electron in the hydrogen–carbon bond must...
Spin–Spin Coupling: Two-Bond Coupling (Geminal Coupling)
The central atom need not be NMR-active because its electrons are affected by the electron polarization of the spin-active atoms. However, spin information is transmitted less effectively than in one-bond coupling, and 2J values are usually weaker than 1J values. The energy of...
