在初级保健中,关于男性对BRCA1/2遗传测试的认识的独特观点
Caryn Scheinberg Andrews1, Istabraq Ibrahim2, Yael Ben Baruch2
1Faculty of Medicine, Hadassah Henrietta Szold School of Nursing, Hebrew University, Jerusalem, Israel. caryn.andrews@mail.huji.ac.il.
男人不知道BRCA1/2基因突变,尽管有家族癌症史. 医疗保健提供者是通过家庭病史评估和遗传咨询来识别患前列腺,胰腺和乳腺癌的风险人群的关键.
科学领域:
- 在瘤学瘤学.
- 遗传学 遗传学 是一个
- 公共卫生 公共卫生
背景情况:
- 患有BRCA1/2突变的男性面临前列腺,胰腺和乳腺癌的风险增加.
- 目前对这些男性的查和风险评估建议尚未得到充分确立.
- 关于男性对BRCA1/2突变及其相关健康影响的理解的研究有限.
研究的目的:
- 评估男性对BRCA1/2遗传测试的看法.
- 评估对癌症风险的认识,感知到的严重性和易感性.
- 确定有关遗传突变的男性健康信息的主要来源.
主要方法:
- 对234名没有个人癌症病史或已知的BRCA1/2状态的男性进行了一项横截面调查.
- 该调查评估了人们对易感性,严重性,个人风险和信息来源的看法.
- 收集了关于家族癌症史和对BRCA1/2状态的认识的数据.
主要成果:
- 几乎所有参与者 (97%) 将医疗保健提供者作为他们主要的健康信息来源.
- 尽管69%的人报告了家族癌症史,58%的人不知道他们或他们的家庭的BRCA1/2状态,通常是由于对BRCA1/2.2缺乏知识.
- 虽然52%的人认为前列腺癌一般具有高风险,但只有22%的人认为他们的个人风险很高.
结论:
- 大多数男性对BRCA1/2基因突变及其影响缺乏认识.
- 通过评估家族癌症史,初级保健提供者对于识别有风险的男性至关重要.
- 加强由提供者领导的教育和指导对于潜在的BRCA1/2-相关风险的男性癌症查和监测至关重要.
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