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Updated: Feb 13, 2026

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在卵巢癌中,prolyl-isomerase Pin1 通过调节 Notch3 的稳定性和功能来驱动的抗性

Maria Valeria Giuli1, Angelica Mancusi2, Bianca Natiello3

  • 1Department of Medico-Surgical Sciences and Biotechnology, Sapienza University of Rome, Laboratory affiliated with Istituto Pasteur Italia- Fondazione Cenci Bolognetti, Latina, Italy.

Journal of experimental & clinical cancer research : CR
|February 12, 2026
PubMed
概括

Pin1/Notch3轴驱动高度血清性卵巢癌 (HGSOC) 的抗性. 准这个轴使瘤重新对化疗敏感,为HGSOC治疗提供了一个新的策略.

关键词:
在HGSOC中,HGSOC是什么?没有3ch3 标记.针对Pin1的目标定位金的药物耐药性 金的药物耐药性

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