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Updated: Feb 13, 2026

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NLK促进了卡斯帕-8的激活,以驱动巨细胞在败血症中的PANoptosis

Yun Xia1, Ren-Qi Yao2, Hui-Fan Liu1

  • 1Department of Anesthesiology, Zhongnan Hospital of Wuhan University, Wuhan, China.

Clinical and translational medicine
|February 12, 2026
PubMed
概括

尼莫样酶 (NLK) 调节巨细胞的PANoptosis,这是败血症中的细胞死亡程序. 抑制NLK可以减少炎症性细胞死亡,器官损伤,并在败血症模型中改善存活率.

关键词:
卡斯帕-8的使用情况类似尼莫的激酶这就是PANoptosis.炎症性细胞死亡巨细胞是一个巨细胞.这是一种血症.

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