基于放射学对抗增强乳房造影的良性和恶性乳房质量的区分:使用开源工具的可复制工作流程
Aykut Teymur1, Sibel Kul2, Ramazan Özgür Doğan3
1University of Health Sciences Türkiye, Antalya City Hospital, Clinic of Radiology, Antalya, Türkiye.
Diagnostic and interventional radiology (Ankara, Turkey)
|February 12, 2026
概括
用对比度增强乳房扫描 (CEM) 图像的放射学分析有效地区分良性与恶性乳房质量. 这种方法,使用重组CEM图像和机器学习,显示了改善乳腺癌诊断的希望.
科学领域:
- 医疗成像医学成像
- 人工智能在医学中的应用
- 放射学 放射学是指放射学
背景情况:
- 乳腺癌的诊断依赖于对良性和恶性质量的准确区分.
- 与对比度增强的乳房显微镜 (CEM) 为乳腺病变的特征提供了有价值的信息.
- 放射学为诊断目的提取成像特征提供了一种定量方法.
研究的目的:
- 为了区分良性和恶性乳腺质量,使用放射性特征从低能和重组CEM图像.
- 评估各种机器学习分类器的诊断性能,用于乳腺质量分类.
- 评估开源工具在CEM分析的放射学工作流中的实用性.
主要方法:
- 对接受CEM的145名患者进行了回顾性分析.
- 从手动细分的感兴趣区域提取放射性特征,用于低能和重组CEM图像.
- 使用开源工作流 (ITK-SNAP,PyRadiomics) 和机器学习分类器,具有10倍交叉验证和独立测试集.
主要成果:
- 合体学习实现了两种图像类型的最高诊断性能.
- 再组合的CEM图像与集体学习产生了91.8%的精度和0.978.97的AUC.
- 对于不同的分类器,观察到高灵敏度和特异性,集体学习和神经网络表现出最佳性能.
结论:
- 对CEM图像的放射学分析有效地区分良性和恶性乳腺质量,可能提高诊断准确性.
- 使用重组CEM图像和开源工具的放射学工作流可以补充传统的解释,并帮助进行非侵入性损伤特征.
- 这种方法支持为临床乳腺成像应用开发决策支持工具.
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