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Updated: Feb 13, 2026

Hollow Fiber Bioreactors for In Vivo-like Mammalian Tissue Culture
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Hollow Fiber Bioreactors for In Vivo-like Mammalian Tissue Culture

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通过功能化的平板板和空心纤维解构深度过器对AAV2清晰度进行电荷控制的机械评估

Mara Baughman-Leach1, Mattie Brock1, Malgorzata Chwatko1

  • 1Department of Chemical and Materials Engineering, University of Kentucky, Lexington, Kentucky, USA.

Biotechnology and bioengineering
|February 12, 2026
PubMed
概括

这项研究开发了一个深度过平台,以优化腺相关病毒 (AAV) 澄清. 通过pH值操纵膜电荷显著影响AAV恢复和基因疗法制造中的杂质去除.

关键词:
深度过的深度过方法基因治疗的基因疗法的纤维是空的纤维.具有pH响应性的病毒载体病毒载体

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