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评估气候相关自然灾害对后续前列腺癌死亡率的潜在影响
Alexander P Cole1,2, Zhiyu Qian1,2, Yu-Jen Chen2
1Department of Urology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Cancer medicine
|February 12, 2026
概括
气候灾害显著增加前列腺癌死亡率,灾难发生两年后的死亡率上升了28%. 这凸显了癌症护理对环境破坏的脆弱性.
科学领域:
- 环境健康 环境健康
- 在瘤学瘤学.
- 公共卫生 公共卫生
背景情况:
- 与气候相关的事件破坏了医疗保健系统,可能会加剧癌症的结果.
- 前列腺癌的重大负担和风险范围可能导致治疗延迟,特别是在晚期.
研究的目的:
- 研究气候相关自然灾害对转移性前列腺癌死亡率的影响.
- 评估灾难严重程度和前列腺癌死亡率之间的剂量依赖关系.
主要方法:
- 在受气候灾害 (2012-2018) 影响的SEER支持县中,对被诊断患有转移性前列腺癌的男性 (2010-2020) 的分析.
- 在灾难发生前两年和灾后两年,以年龄为标准的发病率为基础的死亡率 (IBM) 的比较.
- 根据FEMA的援助和与未受影响县的比较,将灾难分为"重大"事件.
主要成果:
- 与指数年相比,前列腺癌IBM率在灾后一年增加了15%,在灾后两年增加了28%.
- 经历"重大"灾害的县显示出更强烈的关联,死亡率分别在1年和2年分别高出21%和35%.
- 在没有暴露的县里没有观察到类似的死亡率模式.
结论:
- 随着气候相关的自然灾害,转移性前列腺癌死亡率的显著增加取决于剂量.
- 潜在的促成因素包括延迟诊断,分散的护理,以及晚期前列腺癌的治疗中断.
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