用尼沃卢马布治疗的患者的症状,症状负担和影响因素
Ferda Akyuz Ozdemir1, Dilek Yildirim2, Melike Celik3
1Fethiye Faculty of Health Sciences, Department of Internal Medicine Nursing, Mugla Sitki Kocman University, Mugla, Turkey.
Immunotherapy
|February 12, 2026
概括
接受尼沃卢马布免疫治疗的患者会出现各种症状,包括皮肤,胃肠道和肺部问题. 适当的营养和避免同时进行化疗可以帮助管理nivolumab的副作用.
科学领域:
- 在瘤学瘤学.
- 免疫治疗是一种免疫疗法.
- 临床研究 临床研究
背景情况:
- 像尼沃卢马布这样的免疫检查点抑制剂在癌症治疗中至关重要.
- 尼沃卢马布的副作用可能会影响患者的生活质量.
研究的目的:
- 在接受尼沃卢马布免疫治疗的患者中评估症状负担.
- 为了确定影响这些症状的因素.
主要方法:
- 描述性,横截面研究.
- 53名接受尼沃卢马布治疗的患者.
- 通过采访和标准化尺度 (ECOG) 收集的数据.
主要成果:
- 常见症状:皮肤毒性 (,干燥),胃肠道问题 (便秘),肺部症状 (疲劳,咳,呼吸障碍),甲状腺功能低下.
- 同时的化疗增加了症状负担.
- 充足的营养与较少/较轻的症状相关.
- 大多数患者保持良好表现状态.
结论:
- 尼沃卢马布症状严重程度与治疗和生活方式因素有关.
- 优化营养和避免并发化疗可能会减轻副作用.
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