在40岁及以上的成年人中,有吸烟史的人群中,电子烟的持续时间和发生率COPD
medRxiv : the preprint server for health sciences
|February 12, 2026
概括
长期使用电子烟可能会增加慢性阻塞性肺病 (COPD) 的风险,在现有呼吸道症状的前吸烟者中. 优先考虑戒烟和戒烟支持对高风险个人至关重要.
科学领域:
- 肺部病理学 肺部病理学
- 公共卫生 公共卫生
- 控制烟草的控制方式
背景情况:
- 慢性阻塞性肺病 (COPD) 是美国的主要健康问题,主要是由吸烟引起的.
- 电子烟被推销为更安全的替代品,但它们对吸烟者的COPD风险的长期影响尚不清楚.
研究的目的:
- 评估电子烟使用时间和美国成年人有吸烟史的新COPD诊断之间的联系.
- 调查基线呼吸道症状是否影响这种关联.
主要方法:
- 来自烟草和健康 (PATH) 人口评估研究 (第4至第7波) 的纵向数据分析.
- 包括40岁以上的美国成年人,他们目前或曾经吸烟.
- 评估发生的COPD和随时间变化的电子烟使用时间,调整为共变量.
主要成果:
- 在4895名参与者中,长时间使用电子烟与患有原始呼吸道症状的人群中,COPD风险增加有关 (AHR:1.28).
- 在没有基线呼吸道症状的个体中,电子烟使用时间和COPD风险之间没有发现显著的关联 (AHR: 1.01).
- 在控制累积香烟暴露和其他风险因素后,研究结果仍然强大.
结论:
- 长时间使用电子烟可能会增加患有呼吸系统脆弱性的个体的COPD风险.
- 虽然戒烟是一种减少危害的策略,但优先考虑戒烟和对高风险个体的支持至关重要.
- 需要对不断发展的电子烟产品和使用模式进行进一步的研究.
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