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Updated: Feb 13, 2026

Evaluation of Motor Impairment in C. elegans Models of Amyotrophic Lateral Sclerosis
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转录形状分析揭示了在肌缩侧面硬化症中错误拼接和基因融合

Huilin Xu, Tiziana Petrozziello, Adel Boudi

    medRxiv : the preprint server for health sciences
    |February 12, 2026
    PubMed
    概括

    肌缩性侧面硬化症 (ALS) 转录组显示广泛的拼接错误,而不仅仅是基因表达的变化. 这些错误,包括新的RNA融合,为这种神经退行性疾病提供了新的治疗点.

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