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Updated: Feb 13, 2026

Efficient Generation and Editing of Feeder-free IPSCs from Human Pancreatic Cells Using the CRISPR-Cas9 System
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Efficient Generation and Editing of Feeder-free IPSCs from Human Pancreatic Cells Using the CRISPR-Cas9 System

Published on: November 8, 2017

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克里斯普尔-MiX:一个聚合的单链捐赠者策略,以提高人类iPSC中的HDR效率

Rachel Baum1,2, Narasimha Telugu3, Arne A N Bruyneel1,2

  • 1Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.

Molecular therapy. Nucleic acids
|February 12, 2026
PubMed
概括

研究人员开发了CRISPR-MiX,这是一种新的方法,可以显著提高人类诱导多能干细胞 (iPSC) 的同质导向修复 (HDR) 效率,用于精确的基因组编辑和疾病建模.

关键词:
克里斯普尔-Cas9是什么意思DNA 断裂 发生 DNA 断裂.修复DNA的修复DNA的修复MT:RNA/DNA编辑 编辑心肌病性心脏病 - 心肌病性心脏病疾病建模 疾病建模基因组编辑 基因组编辑同质性导向的维修是指导维修.这些是iPSCs.多能干细胞是一种多能干细胞.这就是SSODNN.

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