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隔离,识别和敏感性概况的Bacillus spp. 在同时感染呼吸道病毒时
Angelica de Lima das Chagas1, Joilma Cruz da Silva Araújo2, Jose Daniel Goncalves Vieira3
1Health Science Post Graduation, Medical College, Federal University of Goias, Goiania, Brazil.
经常被忽视的细菌物种在患有病毒性呼吸道感染的儿科重症监护患者中被发现. 敏感性测试揭示了万科米辛,伊米皮涅姆,红红素和西普罗夫洛克萨的有效性.
科学领域:
- 儿童传染病 儿童传染病
- 微生物学 微生物学
- 关键护理医学 关键护理医学
背景情况:
- 二次性细菌感染会恶化病毒性呼吸道疾病,增加发病率和死亡率.
- COVID-19和其他流行病突出显示了共感染的影响.
- 细菌物种通常被认为是环境污染物,关于它们在儿童呼吸道感染中的作用的数据有限.
研究的目的:
- 调查细菌物种在重症监护病房中患有病毒性呼吸道感染的儿科患者的患病率.
- 为了确定这些细菌分离物的抗微生物敏感性模式.
- 评估细菌物种在重症儿科呼吸病例中的临床相关性.
主要方法:
- 对659个患有呼吸道症状的住院儿童的呼吸道样本进行了分析.
- 使用BHI介质确定并通过MALDI-TOF确认的细菌共感染.
- 通过Kirby-Bauer方法按照EUCAST指导方针进行的抗菌敏感性测试.
主要成果:
- 细菌种类占细菌共感染的12.05% (20/166).
- 在患有呼吸道同胞性病毒 (55%) 的患者中观察到细菌分离物占主导地位.
- 对于万科米 (85%),伊米 (80%),红红 (70%) 和西普罗夫洛克萨 (65%) 发现了较高的敏感率.
结论:
- 细菌物种可能在儿科病毒共同感染中发挥临床显著作用,特别是在严重的呼吸道疾病中.
- 针对细菌菌种的常规抗微生物敏感性测试对于优化重症监护治疗至关重要.
- 这项研究为进一步研究儿童群体中细菌毒性和耐药机制的基础数据提供了基础数据.
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