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在末期角膜失明中使用耳膜软骨增强的Mihe (MIOK) KPro:一个开放的,非随机的试验

Qun Wang¹, Yuqi Wang¹, Mei Ge¹

¹Department of Ophthalmology, Chinese PLA General Hospital, Beijing, China.

Advances in ophthalmology practice and research

|February 12, 2026

概括

带有软骨增强的米赫角膜假体 (MIOK) 为重度角膜失明患者恢复视力提供了安全有效的解决方案. 这种创新方法显示了高保留率和显著的视力敏度改善.

科学领域:

眼科医生眼科眼科
再生医学是一种再生医学.
生物材料科学生物材料科学

背景情况:

双边末期角膜失明呈现显著的视力损伤.
在这些患者中,常规的角膜手术和标准的波士顿I型角膜假体植入通常是禁忌的.
需要新的假肢解决方案来进行视觉康复.

研究的目的:

为了评估Mihe角质假肢 (MIOK) 的有效性和安全性,当它被自主耳性软骨加强时.
评估双边末期角膜失明患者的视觉结果和并发症率.

主要方法:

进行了一项前性,单中心,单臂,非随机临床试验.
患有传统手术禁忌的患者接受了两阶段的Mihe Kpro植入.
在手术过程中,使用了自身耳软骨来加强角膜组织.

主要成果:

35名患者完成了MIOK植入,在平均68.8个月的随访期间,其高保留率为97.2% (34/35).
在92%的眼睛中,最佳校正视敏度 (BCVA) 改善到20/200或更好.
常见的并发症包括纤维血管组织过度生长 (14.3%) 和黄斑胀 (14.3%).

结论:

用自主耳软骨增强的Mihe角质假肢是视觉康复的有效和安全选择.
这种方法为双边末期角膜失明患者提供了可行的解决方案,这些患者的治疗选择有限.

关键词:

耳部软骨是一种耳部软骨.自身免疫性疾病是一种自身免疫性疾病.化学烧伤是因为化学烧伤.最终阶段的角膜失明.最终阶段的眼睛干燥.凯拉托假体是指一个假体.这就是MIOKIOK的意义.这就是米赫·米赫·米赫.

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