在LVAD患者中发生大动脉根血栓的发生率和临床影响:单中心体验
Mehmet Karahan1, Sinan Sabit Kocabeyoğlu1, Doğan Emre Sert1
1Clinic of Cardiovascular Surgery, Ankara Bilkent City Hospital, Ankara, Türkiye.
Turk gogus kalp damar cerrahisi dergisi
|February 12, 2026
概括
在左心室辅助器件 (LVAD) 患者中,大动脉根栓塞 (ART) 可能未被充分认识到. 然而,这项研究发现ART对LVAD患者的死亡率或重大不良事件没有显著的影响.
科学领域:
- 心血管医学 心血管医学
- 医疗器械 医疗器械
- 血栓形成研究研究
背景情况:
- 大动脉根栓塞 (ART) 是左心室辅助器件 (LVAD) 患者的一种已知的并发症.
- 了解与ART相关的临床结果对于管理LVAD患者至关重要.
- 治疗ART的诊断可能不足,可能导致不良的心脏和末端器官影响.
研究的目的:
- 评估在接受左心室辅助装置 (LVAD) 后发展大动脉根血栓症 (ART) 的患者的临床结果.
- 在LVAD群体中确定ART和不良事件之间的关联.
主要方法:
- 在2020年1月至2022年3月期间植入成人LVAD患者的回顾性分析.
- 在有和没有ART的患者之间对手术前数据和出院后综合结果的比较.
- 综合结果包括脑血管事件,血栓,心肌梗塞,栓塞事件,出血,右心室衰竭和死亡率.
主要成果:
- 在44名LVAD患者中,20名 (45%) 在出院后发展了ART,血栓形成发生在59天的中位数.
- 在50%的ART病例中,血栓形成的主要部位是非冠状动脉尖端.
- 组之间在复合结果 (p=0.276),死亡率 (p=0.814),出血 (p=0.808) 或VR衰竭 (p=0.197) 中没有发现显著差异.
结论:
- 大动脉根栓塞 (ART) 是LVAD患者经常发现的发现.
- 尽管发生,但ART在这个队列中没有显著增加死亡率或重大不良事件.
- 密切监测和管理LVAD患者是必不可少的,即使没有显著的ART相关并发症.
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