饮食习惯,口腔微生物群和青少年牙之间的联系
Haiyan Yue1, Pei Shen2, Qiumin Huang1
1State Key Laboratory of Genetic Engineering, Human Phenome Institute and School of Life Sciences, Fudan University, 2005 Songhu Road, Shanghai, 200438 China.
Phenomics (Cham, Switzerland)
|February 12, 2026
概括
饮食不良会影响青少年的口腔健康. 这项研究将含糖食物摄入量,特定的口腔细菌和牙损伤联系在一起,揭示了饮食如何通过口腔微生物组影响牙.
科学领域:
- 口腔微生物学 口腔微生物学
- 青少年健康 青少年健康
- 饮食科学 饮食科学
背景情况:
- 不理想的饮食习惯,特别是高糖消费,与牙损风险的增加有关.
- 青少年饮食,口腔微生物群和牙之间的复杂关系尚未完全理解.
研究的目的:
- 研究饮食习惯,口腔微生物群组成和青少年牙损伤之间的综合关联.
- 探索口腔细菌在饮食 - 病关系中的潜在调解作用.
主要方法:
- 通过食物频率调查问卷收集的饮食数据.
- 由牙医评估的牙健康状况.
- 使用16S核糖体RNA测序对421名青少年进行唾液微生物群分析.
- 分析包括微生物组成差异和中介分析.
主要成果:
- 在患有牙和没有牙的青少年之间发现了口腔微生物组成的显著差异,与成年人群的发现一致.
- 19个属的相对丰度与牙损伤有关,包括在高糖消费者中丰富Prevotella和Veillonella.
- 某些属,如Staphylococcus和Paludibacteraceae F0058,可能部分调解饮食和牙损伤之间的联系.
结论:
- 口腔微生物群在调解青少年饮食习惯和牙损伤之间的关联方面发挥着至关重要的作用.
- 研究结果提供了对饮食影响牙发展的潜在机制的见解.
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