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结膜脆弱性与netarsudil有关的结膜脆弱性

Hursuong Vongsachang¹, Emory Davtyan², Michael M Lin¹

¹Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA.

American journal of ophthalmology case reports

|February 12, 2026

概括

在接受切口手术的玻璃眼患者中使用内塔苏迪尔可能会增加风险. 患者经历了结膜脆弱性,导致手术内和术后并发症,其中四次需要修改.

科学领域:

眼科医生眼科眼科
玻璃眼的手术玻璃眼的手术
眼睛药理学眼睛药理学

背景情况:

尼塔苏迪尔是一种用于治疗青光瘤的Rho-酶抑制剂.
在接受青光眼手术的患者中,以前或目前使用内塔苏迪尔的情况越来越普遍.
尼塔苏迪尔对手术结果的影响需要进一步调查.

研究的目的:

描述以前或目前暴露于内塔苏迪尔的玻璃眼患者的手术前和术后并发症.
为了突出与 netarsudil 使用和切割性玻璃眼手术相关的潜在风险.

主要方法:

六名中度至重度青光眼患者的回顾性病例系列.
患者在暴露于netarsudil.com的同时接受了切割性玻璃眼手术.
在手术期间和手术后记录了并发症.

主要成果:

在五名患者的手术内观察到明显的结膜脆弱性.
手术后的并发症包括管道暴露和漏.
由于并发症,六分之四的患者需要手术修复.

结论:

尼塔苏迪尔暴露可能与结膜脆弱性有关.
这种脆弱性可以在切割性玻璃眼外科手术期间和之后增加并发症的风险.
在使用netarsudil的患者中,可能需要仔细选择患者和手术技术.

关键词:

结合性结合性结合性结合性眼光障碍眼光障碍眼光障碍眼光障碍青光眼的排水装置,是眼光眼的排水装置.在Netarsudil中使用.骨切除术 (TRABECULECTOMY) 是一种切除骨的方法.

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