Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

310
Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
310
Overview of Fatty Acid Metabolism01:28

Overview of Fatty Acid Metabolism

37.2K
Lipids also are sources of energy that power cellular processes. Like carbohydrates, lipids are composed of carbon, hydrogen, and oxygen, but these atoms are arranged differently. Most lipids are nonpolar and hydrophobic. Major types include fats and oils, waxes, phospholipids, and steroids.
Fatty acids are catabolized in a process called beta-oxidation, which takes place in the matrix of the mitochondria and converts their fatty acid chains into two-carbon units of acetyl groups. The acetyl...
37.2K
Preparation of Carboxylic Acids: Overview01:31

Preparation of Carboxylic Acids: Overview

3.8K
There are various methods for the preparation of carboxylic acids. For example, oxidation of primary alcohols or aldehydes using strong oxidizing agents results in a carboxylic acid.  Aldehydes can also be oxidized in the presence of mild oxidizing agents.
3.8K
Acid–Base Titration: Overview01:26

Acid–Base Titration: Overview

19.1K
An acid-base titration is a technique used to determine the concentration of an unknown acid or base, using a titrant of known concentration–either a base for acid titration or an acid for base titration. The process involves gradually adding the titrant, leading to a predictable change in the pH of the solution. This change is plotted on a titration curve, showing how a solution's pH varies with the amount of titrant added. Such curves are instrumental in monitoring the...
19.1K
Carboxylic Acid Derivatives: Overview01:15

Carboxylic Acid Derivatives: Overview

5.4K
Carboxylic acid derivatives are formed by replacing the hydroxyl group of carboxylic acids with a different functional group. The most common carboxylic acid derivatives are:
5.4K
The Citric Acid Cycle: Overview01:37

The Citric Acid Cycle: Overview

23.2K
In aerobic organisms, the citric acid cycle is the second stage of cellular respiration wherein molecules derived from the breakdown of carbohydrates, proteins, and fats are oxidized into carbon dioxide and energy. This process is also known as the tricarboxylic acid (TCA) cycle as the first product of the cycle, citric acid, contains three carboxyl groups in its structure. Alternatively, this cycle is also referred to as the Krebs cycle, in honor of its discoverer Sir Hans Krebs.
The citric...
23.2K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Pediatric head injury in the emergency department: balancing radiation risk, missed diagnoses, and decision-rule evolution.

International journal of emergency medicine·2026
Same author

Bilateral Persistent Sciatic Artery With Unilateral Thrombosis: A Rare Case of Acute Limb Ischemia Successfully Managed With Endovascular Intervention.

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions·2026
Same author

A rare case of pregnancy-associated thrombotic thrombocytopenic purpura.

Oxford medical case reports·2026
Same author

Effectiveness of telerehabilitation in patients with post-COVID-19: an updated systematic review and meta-analysis of randomized controlled trials.

BMC pulmonary medicine·2026
Same authorSame journal

Efficacy and Safety of Tranexamic Acid in Pediatric Trauma: A Systematic Review and Meta-Analysis.

The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG·2026
Same author

Refractory Shock in Pediatric Emergency Departments: Challenges and Innovations in Early Escalation: A Narrative Review.

Sage open pediatrics·2026

相关实验视频

Updated: Feb 13, 2026

Author Spotlight: Non-Surgical Treatment of Melasma– Microneedling with Tranexamic Acid
04:12

Author Spotlight: Non-Surgical Treatment of Melasma– Microneedling with Tranexamic Acid

Published on: January 19, 2024

1.6K

儿科护理中的特兰胺酸:全面概述

Mohammed Alsabri1, Mayar M Aziz2, Karim Fahmy3

  • 1Department Of Emergency Medicine, Al-Thawra Modern General Hospital, Sanaa, Yemen and Pediatric Emergency Department, St. Christopher's Hospital for Children, Philadelphia, PA (MA) USA.

The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG
|February 12, 2026
PubMed
概括
此摘要是机器生成的。

特兰胺酸 (TXA) 对儿科出血有效,但需要更多关于剂量,安全性和指导方针的研究. 进一步的研究和标准化的协议对于它在儿童的最佳使用至关重要.

关键词:
这是一种抗纤维素分析剂.发生出血 发生出血血液静止 血液静止 血液静止儿科护理 儿科护理特兰克萨姆酸是什么意思一个创伤的创伤创伤.

更多相关视频

Author Spotlight: Developing a Safer and More Efficient Treatment Protocol for Wasting Marmoset Syndrome (WMS)
03:07

Author Spotlight: Developing a Safer and More Efficient Treatment Protocol for Wasting Marmoset Syndrome (WMS)

Published on: July 12, 2024

1.7K
Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis
05:56

Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis

Published on: August 29, 2025

589

相关实验视频

Last Updated: Feb 13, 2026

Author Spotlight: Non-Surgical Treatment of Melasma– Microneedling with Tranexamic Acid
04:12

Author Spotlight: Non-Surgical Treatment of Melasma– Microneedling with Tranexamic Acid

Published on: January 19, 2024

1.6K
Author Spotlight: Developing a Safer and More Efficient Treatment Protocol for Wasting Marmoset Syndrome (WMS)
03:07

Author Spotlight: Developing a Safer and More Efficient Treatment Protocol for Wasting Marmoset Syndrome (WMS)

Published on: July 12, 2024

1.7K
Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis
05:56

Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis

Published on: August 29, 2025

589

科学领域:

  • 儿科急救医学 儿科急救医学
  • 血液学 血液学 血液学
  • 药理学 药理学 是一个学科.

背景情况:

  • 特兰胺酸 (TXA) 是一种血液静止剂,在成人创伤和手术中具有已证明的益处.
  • 它在儿科医学中用于治疗出血的应用研究较少,现有的知识缺口.
  • 不一致的儿科专用临床指南强调需要进一步调查.

研究的目的:

  • 审查TXA在儿童群体中的疗效,药理动力学,剂量和安全性.
  • 识别儿童TXA当前使用的知识差距和不一致性.
  • 为制定TXA管理的标准化儿科协议提供信息.

主要方法:

  • 使用PubMed和谷歌学者进行了有针对性的文献搜索.
  • 关键词包括与TXA疗效,药理动力学,剂量和儿童 (0-18岁) 安全性相关的MeSH术语.
  • 包括1995年至2025年2月间发表的研究.

主要成果:

  • TXA在减少血液损失,输血需求以及改善儿科创伤,手术和紧急情况的生存率方面表现出有效性.
  • 雾化TXA显示出特定条件的潜力,如桃体切除术后出血.
  • 在年龄特定的药理动力学,长期安全性,血栓栓塞风险和风险方面仍然存在重大差距.

结论:

  • 对于儿科出血紧急情况来说,TXA至关重要,改善了生存和结果.
  • 进一步的跨学科研究,标准化的儿科指南和加强提供者培训是必不可少的.
  • 解决知识差距是TXA在不同儿科环境中安全有效实施的关键.