贝切特病和膝盖无血管亡:一个病例报告
Meera Abou Dehn1, Wael Barakeh2, Sati Dib1
1Faculty of Medicine, American University of Beirut, Beirut, Lebanon.
Annals of medicine and surgery (2012)
|February 12, 2026
概括
本病例报告详细介绍了一例罕见的双侧无血管亡 (AVN) 的膝盖在患有贝塞特病 (BD) 的患者. 早期调查BD患者的关节疼痛对于及时诊断和管理像AVN.这样的潜在并发症至关重要.
科学领域:
- 类风湿病学 类风湿病学
- 免疫学 免疫学 免疫学
- 整形外科 整形外科 整形外科
背景情况:
- 贝切特病 (BD) 是一种罕见的自身免疫性血管炎.
- 由于缺乏特定标志物,诊断通常是临床的.
- 血管性亡 (AVN) 是BD极为罕见的并发症,通常是单焦性.
研究的目的:
- 报告一种罕见的双侧膝关节AVN病例,该病例发生在患有BD的患者身上.
- 要强调考虑AVN在BD患者出现关节疼痛的重要性.
- 强调对自身免疫性疾病症状的及时评估和管理.
主要方法:
- 一个36岁的男性患有BD的病例报告.
- 诊断证实了两个膝盖的磁共振成像 (MRI).
- 治疗调整从rituximab到Infliximab. 这是一个很大的变化.
主要成果:
- 患者出现双侧膝关节疼痛.
- 核磁共振成像证实双侧AVN的膝盖.
- 用Infliximab治疗导致疼痛缓解和临床改善.
结论:
- 双侧膝关节AVN是BD患者罕见但可能出现的并发症.
- 在BD患者的关节疼痛中,即使没有使用皮质类固醇,也需要对AVN进行调查.
- 在BD和其他自身免疫性疾病的早期症状评估可以预防严重的并发症.
相关概念视频
Endocarditis II: Clinical Features of Infective Endocarditis
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
Peripheral Artery Disease I: Introduction
Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
Peripheral Artery Disease V: Postoperative Nursing Management
During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
Venous Thrombosis IV: Nursing Management
Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
Diabetic Retinopathy
DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...


