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使用常规的血液和生化参数来预测社区获得性肺炎的临床结果

Sibel Karakaya¹, Elif Torun Parmaksiz¹, Eylem Tunçay¹

¹Clinic of Chest Diseases, Sancaktepe Şehit Prof. Dr. İlhan Varank Training and Research Hospital, University of Health Sciences, Istanbul, Türkiye.

Saudi journal of medicine & medical sciences

|February 12, 2026

概括

常规的血液标记物,如淋巴细胞计数和白蛋白,可以预测社区获得性肺炎 (CAP) 患者的死亡率和住院时间. 这些发现有助于在CAP的早期风险分层.

科学领域:

临床医学临床医学
肺部病理学肺部病理学
生物化学生物化学

背景情况:

社区获得性肺炎 (CAP) 是导致住院和死亡的重要原因,特别是在老年人群和并发症患者中.
临床上需要在入院时准确的CAP预后标志物.

研究的目的:

评估常见的血液学和生化标志物在预测CAP患者住院死亡率和住院时间的预后价值.
具体评估的淋巴细胞数量,血清白蛋白,甲,中性粒细胞与淋巴细胞的比率 (NLR),以及C反应蛋白 (CRP) /白蛋白比率 (CAR).

主要方法:

在2022年9月至2023年9月期间入院的526名成年CAP患者的回顾性单中心队列研究.
收集的人口,临床和实验室数据,从摄入值计算NLR和CAR.
利用统计分析,包括相关性和ROC曲线分析,以确定预后准确性.

主要成果:

在医院的死亡率为9.5%. 没有幸存者表现出较低的淋巴细胞和白蛋白水平和较高的CRP,甲,NLR和CAR.
淋巴细胞计数 (AUC=0.794) 和白蛋白 (AUC=0.787) 显示出死亡率的最高预测准确度,其次是前素,NLR和CAR.
CRP,公素,NLR和CAR与住院时间长度正相关.

结论:

淋巴细胞计数,血清白蛋白,前素,NLR和CAR是CAP结果的显著预后标志物.
这些常规测量参数可以帮助早期风险分层和CAP患者的临床决策.

关键词:

专辑中的专辑蛋白.在C-反应性蛋白/白蛋白的比率.在社区获得的肺炎.停留时间的长度.淋巴细胞计数是指淋巴细胞的数量.中性粒细胞与淋巴细胞的比率.这是什么意思? procalcitonin.预后预后预后

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