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推进EAE建模:建立多发性硬化症非百日咳免疫接种协议

Shruti Gupta1, Sreejita Arnab2, Elena Stehle2

  • 1Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA, USA.

Bio-protocol
|February 12, 2026
PubMed
概括

在小鼠中,一种新的实验性自身免疫脑膜炎 (EAE) 模型有效地模仿了无百日咳毒素 (PTX) 的多发性硬化症 (MS) 病理. 这种精细的动物模型通过避免PTX,为临床前多发性硬化症研究提供了更好的相关性.

关键词:
过敏症 过敏症 过敏症 过敏症欧洲电子商务管理局 (EEAE)多发性硬化症是多发性硬化症.神经病变性疼痛 神经病变性疼痛非PTX EAE 的非PTX EAE.百日咳毒素 (PTX) 是一种

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