评估空气污染对孕产妇并发症和分娩结果的多维影响:结构方程建模方法
Boubakari Ibrahimou1, Ning Sun1, Sophie Dabo-Niang2,3,4
1Department of Biostatistics, Florida International University, Miami, FL, 33199, USA.
Hygiene and environmental health advances
|February 12, 2026
概括
对空气污染金属混合物 (PM2.5) 的暴露与妊娠期糖尿病和早产等不良妊娠结果有关. 这项研究强调了依赖时间的效应,以及为胎儿健康解决PM2.5中的尘埃的必要性.
科学领域:
- 环境健康 环境健康
- 生殖流行病学 生殖流行病学
- 毒理学 毒理学 毒理学
背景情况:
- 空气污染,特别是颗粒物 (PM2.5),对公众健康的关注越来越大.
- 暴露于PM2.5中的金属混合物可能会对母亲和胎儿的健康造成风险.
- 了解金属混合物对怀孕结果的具体影响对于有针对性的干预至关重要.
研究的目的:
- 调查暴露于空气中的金属混合物 (PM2.5) 和不良妊娠结果之间的直接和间接关联.
- 为了检查这些关系跨越不同的妊娠阶段.
- 阐明金属混合物暴露影响怀孕并发症和分娩结果的途径.
主要方法:
- 使用结构方程建模,采用佛罗里达州两个县的46,829例出生数据 (2021) 和空气质量系统数据.
- 在PM2.5中构建的潜在金属混合物,包括,,铁,,,,和.
- 分析了对妊娠前,妊娠期糖尿病,低出生体重和早产风险的影响.
主要成果:
- 确定了一个隐藏的变量,代表PM2.5中的七种金属.
- 金属混合物暴露的直接影响观察到妊娠糖尿病和早产 (1st/2nd三个月),低出生体重 (1st三个月),和孕前 (第二个三个月).
- 总效应分析揭示了低出生体重 (第一季度) 和孕前 (第二季度) 的掩盖影响,第二季度低出生体重的风险增加了2% (OR=1.02).
结论:
- 在PM2.5金属混合物暴露和不良妊娠结果之间存在时间依赖的关联.
- 这些发现强调了解决PM2.5.5中的尘埃成分的重要性.
- 为了解污染对胎儿健康的影响途径提供了证据.
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