一种使临床和翻译研究团队能够使用来自电子健康记录系统的定制真实世界数据的方法
Thomas R Campion1,2,3,4, Evan T Sholle1,2, Xiaobo Fuld2
1Department of Population Health Sciences, Weill Cornell Medicine, New York, NY, USA.
Journal of clinical and translational science
|February 12, 2026
概括
定制研究数据库 (RDR) 集成来自电子健康记录 (EHR) 的真实世界数据 (RWD),增强临床研究. 这种方法结合了发现,收集和分析工具,支持学术成果和质量改善计划.
科学领域:
- 临床和翻译科学 临床和翻译科学
- 医疗信息学 医疗信息学
- 数据管理数据管理
背景情况:
- 来自电子健康记录 (EHR) 的真实世界数据 (RWD) 需要针对各种研究需求进行定制转换.
- 现有的工具和调查人员的财务承诺可以促进RWD在学术医疗中心的利用.
研究的目的:
- 评估一种解决方案,以增加RWD在临床和转化研究中的使用.
- 评估定制研究数据库 (RDR) 的可扩展性和监管合规性.
主要方法:
- 在威尔康奈尔医学院 (WCM) 使用i2b2,REDCap和微软SQL服务器实现定制RDR.
- 为RDR管理提供中央IT的补贴,并为启动和维护提供调查人员的财务承诺.
主要成果:
- 从2013年到2025年,超过17个定制的RDR在各种专业领域推出.
- RDRs促进了学术成果,包括出版物和赠款,并支持了质量改进活动.
结论:
- 定制的RDR可以从EHR和其他RWD来源提供适合目的的数据集.
- RDRs的演变意味着研究人员和IT之间的数据伙伴关系的转变,提高了研究团队的RWD利用率.
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