过:一个基于拼图的生物信息学介绍
Michele C Morris1, Madelene Loftin1, Malcolm Parker1
1HudsonAlpha Institute for Biotechnology.
概括
FILTERED是一款新的游戏,通过拼图教导高中生生物信息学核心概念. 该游戏显著提高了学生的生物信息学知识,尽管职业兴趣略有下降.
科学领域:
- 生物信息学是一种生物信息学.
- 计算生物学 计算生物学
- 基因组分析 基因组分析
背景情况:
- 介绍生物信息学资源有限,阻碍了科学教育.
- 生物信息学和计算生物学在现代生物研究中至关重要.
- 对计算生物学技能的需求日益增长.
研究的目的:
- 通过引人入胜的教育工具向高中生介绍基本的生物信息学概念.
- 发展对生物信息学过程的概念理解,而不是专注于编程.
- 为了解决入门生物信息学资源的短缺问题.
主要方法:
- 开发了"FILTERED",这是一款以漫画图形为基础的在线,基于拼图的教育游戏.
- 模拟了用于DNA序列分析和生物问题解决的计算工具的应用.
- 涵盖了关键的生物信息学概念:质量评分,序列对齐,保存分析,比较基因组学和变体识别.
主要成果:
- 观察到学生生物信息学知识的统计学上显著改善.
- 学生和教师报告说,他们对游戏有很高的参与度和乐趣.
- 游戏后,人们注意到自己对生物信息学职业的兴趣意外下降.
结论:
- FILTERED是提高高中生生物信息学教育的有效工具.
- 游戏成功地使复杂的生物信息学概念变得易于理解和引人入胜.
- 可能需要进一步的研究来了解对职业兴趣的影响.
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