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通过mTOR/Stat3信号通路调节铁亡,APOE可以抑制骨髓瘤

Xiangyang Cheng1, Chong Bian1, Yiming Zhang1

  • 1Department of Orthopedics, Minhang Hospital, Fudan University, Minhang District, Shanghai, China.

Archives of medical science : AMS
|February 12, 2026
PubMed
概括

脂蛋白E (APOE) 的过度表达通过促进铁和自来抑制骨髓瘤 (OS) 的生长. 这一发现为治疗这种侵袭性骨癌提供了有前途的治疗标.

关键词:
在这里,APOEOE是APOE.自自是自的过程.铁性化 (ferroptosis) 是一种在mTOR/Stat3信号通道上.骨质肉瘤是骨质肉瘤的一种疾病.

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