人工智能驱动的抗癌发现
Junrui Wu1, Shuaiqi Ji1, Kashif Iqbal Sahibzada2,3,4
1College of Food Science Shenyang Agricultural University, National Agricultural Environmental Microbial Germplasm Resource Bank, Liaoning Engineering Research Center of Food Fermentation Technology, Shenyang Key Laboratory of Microbial Fermentation Technology Innovation Shenyang PR China.
概括
人工智能 (AI) 通过克服传统查局限性,加速发现抗癌 (ACP). 一个新的AI框架提高了ACP选效率和临床翻译,解决了模型解释性和验证差距.
科学领域:
- 生物技术是生物技术.
- 计算生物学 计算生物学
- 药物发现 药物发现 药物发现
背景情况:
- 癌症仍然是一个重大的全球健康挑战,目前治疗方法的局限性.
- 抗癌 (ACP) 由于其选择性和低毒性,为新药开发提供了一个有希望的途径.
- 传统的ACP选方法是低效,昂贵和复杂的,阻碍了高通量应用.
研究的目的:
- 系统地审查68个AI模型的优点和局限性.
- 提出基于人工智能的ACP查综合框架,以提高效率和临床翻译.
- 将多学科和生物技术纳入人工智能框架,以改善非洲国家和地区的发展.
主要方法:
- 系统审查和总结68个AI模型用于ACP选.
- 开发基于人工智能的新型ACP选框架,包括数据组织,特征提取,模型构建,可解释性分析和实验验证.
- 将多主题和生物技术与人工智能查框架相结合.
主要成果:
- 人工智能模型在提高非洲和非洲国家/地区查效率和准确性方面显示出巨大的潜力.
- 现有的ACP查人工智能模型往往缺乏可解释性和实验验证,这影响了它们的实用性.
- 拟议的AI框架通过结合可解释性分析和实验验证来解决这些局限性.
结论:
- 开发的基于AI的ACP查框架加速了新型抗癌的识别和开发.
- 这一框架提高了查效率,并促进了人工智能发现的ACP的临床应用.
- 将人工智能与多领域和生物技术相结合,对于将人工智能选择的非洲国家和地区转化为有效的临床疗法至关重要.
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