神经子空间重组反映了基于价值的决策
bioRxiv : the preprint server for biology
|February 12, 2026
概括
大脑的决策重新组织了在侧面前额叶皮质 (LPFC) 中选项的表示方式. 选择的选项被扩展并旋转成一个子空间,代表正确的动作,改进动作选择.
科学领域:
- 神经科学是一个神经科学.
- 认知神经科学 认知神经科学
- 决策神经科学 决策神经科学
背景情况:
- 基于价值的决策包括比较选项和沟通选择以指导行为.
- 基于价值的决策的神经回路是已知的,但决策如何影响选项表示的理解较少.
研究的目的:
- 研究决策如何在侧面前额皮层 (LPFC) 中动态重组选项的神经表示.
- 了解决策促进行动选择的神经机制.
主要方法:
- 从非人类灵长类 (NHPs) 的LPFC记录的神经活动.
- NHP 在工作内存中保存了两个顺序呈现的选项值对,并选择了价值更高的选项.
- 在决定之前和之后分析了选择和未选择选项的神经表征.
主要成果:
- 选择和未选择选项的神经表现在决策后旋转成直角子空间.
- 选择选项的表示扩展并与一致的行动子空间保持一致,无论呈现顺序如何.
- 在做出决定之前,顺序呈现的选项的表述被单独维护.
结论:
- 决策动态重组LPFC中的神经表示.
- 这种神经子空间重组有助于选择性和高效地读取所选择的动作.
- 在将基于价值的决策转化为可采取行动的表现方面,LPFC发挥着关键作用.
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