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Updated: Jun 5, 2026

Consensus Brain-derived Protein, Extraction Protocol for the Study of Human and Murine Brain Proteome Using Both 2D-DIGE and Mini 2DE Immunoblotting
10:51

Consensus Brain-derived Protein, Extraction Protocol for the Study of Human and Murine Brain Proteome Using Both 2D-DIGE and Mini 2DE Immunoblotting

Published on: April 10, 2014

单板蛋白质组学揭示了阿尔茨海默病中粉样微环境的组成和动态

Mengqi Chu, Ju Wang, Jay M Yarbro

    bioRxiv : the preprint server for biology
    |February 12, 2026
    PubMed
    概括

    阿尔茨海默病的粉样斑块是具有定义蛋白质组 (粉样组) 的动态枢纽. 这项研究揭示了早期的免疫和 lysosomal 激活,其次是RNA 处理和突触通路参与,将斑块积累与细胞事件联系起来.

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