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Updated: Feb 13, 2026

CRISPR-Mediated Reorganization of Chromatin Loop Structure
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通过CTCF介导的染色质组织的结构基础

Manuel Osorio Valeriano, Alexander C Stone, Masahiro Nagano

    bioRxiv : the preprint server for biology
    |February 12, 2026
    PubMed
    概括

    CCCTC结合因子 (CTCF) 通过核细胞 oligomerization 组织色素结构,这对于基因组相互作用和细胞分化至关重要. 破坏CTCF相互作用会影响基因表达和细胞发育.

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