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Updated: Feb 13, 2026

Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics
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在结肠直肠癌中准HIF-2α揭示了胆固醇生物合成依赖的ferroptotic脆弱性

Prarthana J Dalal, Rashi Singhal, Boyan Hu

    bioRxiv : the preprint server for biology
    |February 12, 2026
    PubMed
    概括

    结合低氧诱导因子2α (HIF-2α) 抑制与胆固醇生物合成阻断剂,如他类药物,有效抑制结肠直肠癌 (CRC) 的生长,并通过诱导铁亡促进细胞死亡.

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