中性粒细胞衍生反应性氧物种介导多克索鲁比诱导的心脏毒性和骨肌肉病变

Kasia Dzierlega1, Amro M Soliman1,2, Huachen Chen3

  • 1Department of Medical Microbiology and Immunology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2R3, Canada.

概括

多克索鲁比化疗会通过中性粒细胞引起肌肉损伤. 阻止这些免疫细胞或它们的活性氧物种 (ROS) 生产可以防止这种化疗副作用.

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