Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Depth Perception and Spatial Vision01:15

Depth Perception and Spatial Vision

2.1K
Depth perception is the ability to perceive objects three-dimensionally. It relies on two types of cues: binocular and monocular. Binocular cues depend on the combination of images from both eyes and how the eyes work together. Since the eyes are in slightly different positions, each eye captures a slightly different image. This disparity between images, known as binocular disparity, helps the brain interpret depth. When the brain compares these images, it determines the distance to an object.
2.1K
Conservation of Protein Domains Over Different Proteins02:26

Conservation of Protein Domains Over Different Proteins

14.7K
Protein domains are small structurally independent units that are part of a single amino acid chain.  Although these domains are often structurally independent, they may rely on synergistic effects to perform their functions as part of a larger protein. Protein domains may be conserved within the same organism, as well as across different organisms.
A limited set of protein domains often duplicate and recombine during evolution. These domains can be organized in different combinations to...
14.7K
Three Developmental Domains01:29

Three Developmental Domains

1.2K
Human development is typically examined across three main domains: physical, cognitive, and socio-emotional. These domains represent the significant areas of change and continuity throughout the lifespan, from infancy to late adulthood.
Physical Development
Physical processes, also known as maturation, encompass the biological changes that occur across an individual's life. These changes begin with genetic inheritance and continue through various stages, including growth in height and weight,...
1.2K
Membrane Domains01:18

Membrane Domains

7.2K
The membrane domains concentrate specific lipids and proteins at one place within the membrane, which helps in cell signaling, adhesion, and other critical cellular processes. These domains can differ in size, composition, function, and lifespan.
Protein Domains
The membrane comprises a group of distinct proteins responsible for carrying out a cell's specific function. For example, the plasma membrane of the human sperm, or a single germ cell, contains a unique set of proteins in the...
7.2K
Three-Domain System of Life01:21

Three-Domain System of Life

1.4K
Ribosomal RNA (rRNA) sequence analysis revealed three distinct groups of cells: eukaryotes, bacteria, and archaea. In 1978, Carl R. Woese proposed the concept of domains, a taxonomic level above kingdoms, to differentiate these groups. He suggested that archaea and bacteria, despite their similar appearance, represent separate domains. Domains differ in rRNA, membrane lipid structure, transfer RNA, and antibiotic sensitivity.In this classification, animals, plants, and fungi belong to the...
1.4K
Conservation of Protein Domains02:26

Conservation of Protein Domains

4.2K
4.2K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Multi-trajectory patterns of ADL, cognition, and depression with fall risk: evidence from a longitudinal study in China.

BMC geriatrics·2026
Same author

Antibody-drug conjugates in breast cancer: from mechanism to revolutionizing clinical practice.

Molecular cancer·2026
Same author

Spatially informed reference-free cell-type deconvolution for spatial transcriptomics with SpatialCD.

Genome research·2026
Same author

Perivascular Matrix Densification Dysregulates Angiogenesis and Activates Pro-Inflammatory Endothelial Cells.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

Food environment and cardiovascular kidney metabolic diseases mortality.

NPJ science of food·2026
Same author

Letter regarding "Survival outcomes and prognostic nomogram for primary pulmonary MALT lymphoma and diffuse large B-cell lymphoma: A SEER database study".

Biomolecules & biomedicine·2026
Same journal

Learning Moisture-Induced Damage From Vision: Diffusion Models for Real-Time Monitoring of Additive Manufacturing Processes.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same journal

Intrinsic Dual-Phase Regulated GeSe<sub>2</sub> Nanoparticles Triggered by Ball-Milling Treatment for Photonic Multi-Valued Logic Circuits.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same journal

A Plant Photoregulator-Inspired S-Type Heterojunction System for Diabetic Keratopathy via Tri-Modal Light-Driven Immunometabolic Reprogramming, Tissue Repair, and Antibacterial Activity.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same journal

eEF1G Orchestrates Translation to Ensure Meiotic Progression in Transcriptionally Quiescent Spermatocytes.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same journal

Ultrasound-Recharged Sub-Nanometer Palladium Catalysts for on-Demand and Self-Terminating Bioorthogonal Prodrug Activation in Cancer Therapy.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same journal

Graphene Aerogels With Spherical Pore Structure for Broad Frequency Regulation and Enhanced Low-Frequency Response.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
查看所有相关文章

相关实验视频

Updated: Feb 13, 2026

Mining Spatial Transcriptomics Datasets using DeepSpaceDB
10:16

Mining Spatial Transcriptomics Datasets using DeepSpaceDB

Published on: September 5, 2025

805

空间ESD:空间转录学中的空间集域检测.

Hongyan Cao1,2, Gaiqin Liu1,2, Jingyi Xia1,2

  • 1Department of Health Statistics, Shanxi Provincial Key Laboratory of Major Diseases Risk Assessment, School of Public Health, Shanxi Medical University, Taiyuan, Shanxi, China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|February 12, 2026
PubMed
概括
此摘要是机器生成的。

空间ESD通过整合多种方法来改善空间转录学 (ST) 中的空间域检测. 这种强大的方法提高了准确性和稳定性,可以从组织基因表达数据中获得更好的生物学见解.

关键词:
整体集群集群是指集群集群.多尺度相似性建模的多尺度相似性建模空间聚类是空间聚类.空间域检测空间域检测空间转录学 空间转录学

更多相关视频

Spatially Compact Arrangement of Larval Zebrafish Sections for Spatial Transcriptomic Analysis
07:40

Spatially Compact Arrangement of Larval Zebrafish Sections for Spatial Transcriptomic Analysis

Published on: May 16, 2025

985
Author Spotlight: Exploring Advanced Therapeutic Targets in Osteosarcoma Through Spatial Transcriptomics
07:43

Author Spotlight: Exploring Advanced Therapeutic Targets in Osteosarcoma Through Spatial Transcriptomics

Published on: May 3, 2024

4.5K

相关实验视频

Last Updated: Feb 13, 2026

Mining Spatial Transcriptomics Datasets using DeepSpaceDB
10:16

Mining Spatial Transcriptomics Datasets using DeepSpaceDB

Published on: September 5, 2025

805
Spatially Compact Arrangement of Larval Zebrafish Sections for Spatial Transcriptomic Analysis
07:40

Spatially Compact Arrangement of Larval Zebrafish Sections for Spatial Transcriptomic Analysis

Published on: May 16, 2025

985
Author Spotlight: Exploring Advanced Therapeutic Targets in Osteosarcoma Through Spatial Transcriptomics
07:43

Author Spotlight: Exploring Advanced Therapeutic Targets in Osteosarcoma Through Spatial Transcriptomics

Published on: May 3, 2024

4.5K

科学领域:

  • 基因组学就是基因组学.
  • 生物信息学是一种生物信息学.
  • 计算生物学 计算生物学

背景情况:

  • 空间转录学 (ST) 能够在组织环境中测量基因表达.
  • 由于数据的复杂性和可变的集群方法性能,ST数据中的空间域检测具有挑战性.

研究的目的:

  • 开发一个集体方法,SpatialESD,用于改进ST数据中的空间域检测.
  • 通过整合多种集群方法来提高空间域识别的稳定性和准确性.

主要方法:

  • 空间ESD集成了来自多个空间域检测算法的结果.
  • 该方法捕捉了集群之间的直接共发生和多规模间接关系.
  • 在模拟和现实世界ST数据集 (人类大脑,乳腺,卵巢癌) 上进行的评估.

主要成果:

  • 空间ESD的表现始终优于单个方法和现有的EnSDD整体.
  • 在各种数据集中展示了卓越的集群准确性和稳定性.
  • 促进了下游分析,包括差异性基因表达,轨迹和细胞-细胞相互作用分析.

结论:

  • 空间ESD为ST数据中的空间域检测提供了可靠和有效的解决方案.
  • 该方法通过改进的空间分析提高了对组织组织和疾病机制的理解.
  • 能够从空间转录组学中进行更强大的下游生物发现.