从Chlorella vulgaris衍生的纳米颗粒的生物合成,结构特征和生物评估 乙醇提取物
Alexandra Ivanova1, Mina Todorova1, Dimitar Petrov2
1Department of Organic Chemistry, Faculty of Chemistry, University of Plovdiv, 4000 Plovdiv, Bulgaria.
Nanomaterials (Basel, Switzerland)
|February 12, 2026
概括
使用Chlorella vulgaris提取物的银纳米粒子 (AgNPs) 的绿色合成增强了抗菌和解作用. 这些新型AgNP显示出功能性食品和胃肠道治疗的潜力.
科学领域:
- 生物技术和纳米材料科学 生物技术和纳米材料科学
- 微生物学和药理学 微生物学和药理学
背景情况:
- 众所周知,Chlorella vulgaris微藻具有营养和药用特性.
- 银纳米粒子 (AgNPs) 对于它们的抗微生物和治疗应用具有兴趣.
研究的目的:
- 为了使用Chlorella vulgaris提取物合成绿色AgNP.
- 评估AgNP形成对提取物化学成分,抗微生物,抗氧化剂和解作用的影响.
- 评估这些AgNP的新型解活性.
主要方法:
- 使用乙醇Chlorella vulgaris提取物的AgNPs的绿色合成.
- 使用ATR-FTIR,TEM,XRD,DLS和泽塔潜力的AgNP的表征.
- 对各种微生物的抗微生物活性评估.
- 使用ex vivo器官浴实验对大鼠胃光滑肌肉进行解活动的评估.
主要成果:
- 合成了具有良好的体稳定性的球形AgNP (10-50nm).
- 合成AgNP改变了脂质组成,减少了叶绿素,增加了不和脂肪酸.
- 生物合成的AgNP表现出中度至强度的抗菌和抗真菌活性,特别是针对A. niger和P. chrysogenum.
- AgNPs调节了大鼠胃光滑肌收缩活动和性概况.
结论:
- 来自Chlorella vulgaris的绿色合成AgNP表现出增强的抗菌特性和改变的解活性.
- 这些AgNP显示出在功能性食品,营养药品和胃肠道治疗中应用的潜力.
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