在晚期癌症患者中发现日常症状和幸福感的波动:一种经验抽样方法研究
Joran Geeraerts1, Lara Pivodic1, Kim de Nooijer1
1Vrije Universiteit Brussel (VUB), End-of-Life Care Research Group, Brussels, Belgium.
Palliative medicine
|February 12, 2026
概括
经验采样方法对于晚期癌症患者来说是可行的和可以接受的,有效地捕捉每日症状和幸福感的波动. 这种方法提供了一个有希望的方式来个性化护理和提高生活质量.
科学领域:
- 在瘤学瘤学.
- 数字健康数字健康
- 患者报告的结果
背景情况:
- 晚期癌症患者经常经历各种症状和健康状况下降.
- 使用基于智能手机的调查问卷的经验采样方法 (ESM) 提供了对日常生活经验的详细见解.
研究的目的:
- 评估ESM在晚期癌症患者中的可行性和可接受性.
- 确定ESM在发现每一刻症状和幸福感波动方面的潜力.
主要方法:
- 一项观察性研究,涉及7天ESM期间,每天对症状和福祉进行10次评估.
- 通过响应率评估可行性;通过有关负担,易用性,清晰性和反应性的问卷评估可接受性.
- 用人内部标准偏差来分析症状和幸福感的波动.
主要成果:
- 报名的参与者有40人,其中37人完成了1703项有效评估 (71%的完成率).
- 参与者报告说,负担较低 (M=2.1),使用方便度高 (M=5.6),清晰度高 (M=6.5),反应性最低 (M=1.3).
- 对疲劳 (M=16.7),放松感 (M=13.0) 和活动限制 (M=12.4) 观察到的人体内最大波动.
结论:
- 对于晚期癌症患者来说,ESM是一种可行和可接受的方法,擅长捕捉个体症状和幸福感的变化.
- 通过阐明波动机制,ESM有望增强个性化护理和改善生活质量.
相关概念视频
Extraction: Advanced Methods
1.2K
Metal ions can be separated from one another by complexation with organic ligands–the chelating agent– to form uncharged chelates. Here, the chelating agent must contain hydrophobic groups and behave as a weak acid, losing a proton to bind with the metal. Since most organic ligands used in this process are insoluble or undergo oxidation in the aqueous phase, the chelating agent is initially added to the organic phase and extracted into the aqueous phase. The metal-ligand complex is...
1.2K
Sample Preparation for Analysis: Advanced Techniques
1.5K
Accurate analysis of complex samples often requires advanced preparation techniques to achieve reliable and reproducible results. Samples containing inorganic or organic materials can be challenging to dissolve or decompose effectively. Standard sample preparation methods include acid digestion, fusion, dry ashing, and wet digestion.
Acid digestion with strong acids is commonly used to dissolve inorganic materials that are insoluble (do not dissolve) in water. This method can be useful for...
Acid digestion with strong acids is commonly used to dissolve inorganic materials that are insoluble (do not dissolve) in water. This method can be useful for...
1.5K
Sampling Methods: Sample Types
3.3K
Sampling materials are classified into three main types: solid, liquid, and gas.
Solid samples include a variety of substances, such as sediments from water bodies, soil, metals, and biological tissues. Two standard methods for extracting sediments from water bodies are grab sampling and piston coring. Grab sampling involves using a device to collect a discrete sediment sample from the bottom of a water body with minimal disturbance. Grab samples do not always represent the entire area due to...
Solid samples include a variety of substances, such as sediments from water bodies, soil, metals, and biological tissues. Two standard methods for extracting sediments from water bodies are grab sampling and piston coring. Grab sampling involves using a device to collect a discrete sediment sample from the bottom of a water body with minimal disturbance. Grab samples do not always represent the entire area due to...
3.3K
Convenience Sampling Method
11.7K
Sampling is a technique to select a portion (or subset) of the larger population and study that portion (the sample) to gain information about the population. Data are the result of sampling from a population. The sampling method ensures that samples are drawn without bias and accurately represent the population.
Convenience sampling is a non-random method of sample selection; this method selects individuals that are easily accessible and may result in biased data. For example, a marketing...
Convenience sampling is a non-random method of sample selection; this method selects individuals that are easily accessible and may result in biased data. For example, a marketing...
11.7K
Classical Conditioning in Daily Life
2.3K
Classical conditioning, a fundamental principle of associative learning, explains various phenomena observed in daily life, such as fear development, the placebo effect, taste aversion, and drug habituation. These applications demonstrate the profound impact of associative learning on human behavior and physiological responses.
John B. Watson and Rosalie Rayner famously demonstrated the development of fear through classical conditioning in their experiment with Little Albert. They paired the...
John B. Watson and Rosalie Rayner famously demonstrated the development of fear through classical conditioning in their experiment with Little Albert. They paired the...
2.3K
Sampling Methods: Overview
3.5K
A sample refers to a smaller subset representative of a larger population. In analytical chemistry, studying or analyzing an entire population is often impractical or impossible. Therefore, samples are used to draw inferences and generalize the whole population. The sampling method selects individuals or items from a population to create a sample. Standard sampling methods include random, judgemental, systematic, stratified, and cluster sampling.
In analytical chemistry, the choice of...
In analytical chemistry, the choice of...
3.5K


