Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Acute Kidney Injury II: Pathophysiology01:29

Acute Kidney Injury II: Pathophysiology

1.2K
Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...
1.2K
Kidney Structure01:45

Kidney Structure

75.5K
The kidneys are two large bean-shaped organs located in the upper abdomen. They filter the blood several times a day to remove toxins and rebalance water and electrolytes of the circulatory system via the renal veins. The kidneys receive blood directly from the heart via the renal arteries. These arteries enter the kidney at the hilum, the concave surface of the bean, where they branch and divide into smaller vessels and capillaries.
75.5K
What is Natural Selection?01:32

What is Natural Selection?

129.8K
Natural selection is an evolutionary process in which individuals with survival-promoting traits reproduce at higher rates. These favorable traits become more common within a population or species. Naturally selected traits initially arise via random genetic mutations. In order for selection to occur, there must be variation within a population, the trait controlling the variation must be heritable, and there must be an evolutionary advantage for variation in the trait.
129.8K
Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

3.7K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
3.7K
Hypertension II: Pathophysiology01:29

Hypertension II: Pathophysiology

1.0K
Hypertension is a chronic condition in which the blood's force against artery walls is excessively high, posing risks such as heart disease. The condition's underlying mechanisms involve complex interactions among the cardiovascular, kidney, and autonomic nervous systems.Renin-Angiotensin-Aldosterone System (RAAS): This system significantly influences blood pressure regulation. When blood pressure decreases, the kidneys secrete renin. This enzyme transforms angiotensinogen, a plasma protein,...
1.0K
Pneumonia II: Pathophysiology01:29

Pneumonia II: Pathophysiology

3.1K
The pathophysiology of pneumonia involves the following steps:
3.1K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Complexes of Zinc(II) Chloride with <i>N</i>-Vinyl-, <i>N</i>-Allyl- and <i>N</i>-Propargylimidazoles: Structural, Theoretical and Biological Studies.

Pharmaceuticals (Basel, Switzerland)·2026
Same author

Zinc Signaling in Acute Kidney Injury.

Cells·2026
Same author

BDNF/TrkB Signaling in the Brain-Kidney Axis Under Functional Stress.

Biology·2026
Same author

Comparative Diagnostic Performance of Conventional and Novel Fatty Acid Indices in Blood Plasma as Biomarkers of Atherosclerosis Under Statin Therapy.

Biomedicines·2026
Same author

Senotherapeutics for Brain Aging Management.

Neurology international·2025
Same author

DNA and Histone Modifications Identify a Putative Controlling Element (CE) on the X Chromosome of <i>Sciara coprophila</i>.

Cells·2025

相关实验视频

Updated: Feb 13, 2026

Robot-Assisted Kidney Transplantation
07:30

Robot-Assisted Kidney Transplantation

Published on: July 19, 2021

4.4K

干白素-6在自然和病理生理衰老中的作用

Kerim Mutig1,2,3, Prim B Singh1, Svetlana Lebedeva4

  • 1Department of Biosciences, School of Medicine, Nazarbayev University, Astana 010000, Kazakhstan.

Cells
|February 12, 2026
PubMed
概括

脏衰老与炎症有关,其中IN-6 (IL-6) 发挥着关键作用. 了解IL-6的理解

关键词:
老化的老化 衰老的老化细胞因子 细胞因子炎症导致的炎症.这是一种炎症炎症炎症炎症.互乐金-6是其中的一种.互乐金-6 抑制剂 互乐金-6 抑制剂脏 脏 脏是什么?

更多相关视频

Measuring the Functional Abilities of Children Aged 3-6 Years Old with Observational Methods and Computer Tools
11:29

Measuring the Functional Abilities of Children Aged 3-6 Years Old with Observational Methods and Computer Tools

Published on: June 20, 2020

9.8K
The Mouse Isolated Perfused Kidney Technique
08:19

The Mouse Isolated Perfused Kidney Technique

Published on: November 17, 2016

23.5K

相关实验视频

Last Updated: Feb 13, 2026

Robot-Assisted Kidney Transplantation
07:30

Robot-Assisted Kidney Transplantation

Published on: July 19, 2021

4.4K
Measuring the Functional Abilities of Children Aged 3-6 Years Old with Observational Methods and Computer Tools
11:29

Measuring the Functional Abilities of Children Aged 3-6 Years Old with Observational Methods and Computer Tools

Published on: June 20, 2020

9.8K
The Mouse Isolated Perfused Kidney Technique
08:19

The Mouse Isolated Perfused Kidney Technique

Published on: November 17, 2016

23.5K

科学领域:

  • 老年病学和科.
  • 免疫学和炎症研究研究
  • 慢性疾病病理生理学 慢性疾病病理生理学

背景情况:

  • 随着全球寿命的增加,脏衰老是一个越来越令人担忧的问题.
  • 慢性病 (CKD) 影响超过10%的成年人,通常与代谢和心血管问题有关.
  • 与年龄相关的炎症,由INTERLEUKIN-6 (IL-6) 中介,影响自然衰老和CKD发展.

研究的目的:

  • 为了审查Interleukin-6 (IL-6) 在自然和病理生理性脏衰老中的作用.
  • 在脏衰老的背景下,探索IL-6抑制的潜在脏保护作用.
  • 要突出IL-6的交叉点,炎症和与年龄相关的衰退.

主要方法:

  • 文献综述综合了关于IL-6和衰老的当前知识.
  • 对IL-6参与病理生理学的现有数据的分析.
  • 检查研究IL-6抑制剂及其效应的研究.

主要成果:

  • IL-6是影响脏的与年龄相关的炎症的中心调解者.
  • IL-6与加速脏衰老的心血管和脏疾病有关.
  • 关于专门针对脏衰老的IL-6抑制的数据有限,尽管它在其他脏疾病中显示出希望.

结论:

  • IL-6是将自然衰老与慢性病导致的加速衰老联系起来的关键因素.
  • 需要进一步的研究来澄清IL-6抑制对脏衰老的具体影响.
  • 向IL-6可能为与年龄相关的脏疾病提供治疗潜力.