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Updated: Feb 13, 2026

Examining BCL-2 Family Function with Large Unilamellar Vesicles
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Published on: October 5, 2012

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在应激反应时,WWOX诱导通过溶酶体途径促进Bcl-XL和Mcl-1降解

Yu-Han Su1, Wei Chiang2, Yi-Yu Wang1

  • 1Department of Medical Laboratory Science and Biotechnology, College of Medicine, National Cheng Kung University, Tainan 701401, Taiwan.

Cells
|February 12, 2026
PubMed
概括

压力增加WWOX基因表达,影响细胞死亡途径. 通过溶解体,WWOX促进了Bcl-XL和Mcl-1蛋白的降解,从而加剧了氧化应激.

关键词:
在Bcl-2家族中.lysosome 溶解酶体是如何形成的氧化应激是一种氧化应激.蛋白质降解 蛋白质降解这是一种瘤抑制剂.

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