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大脑-计算机接口控制的脚机器人训练对中风后运动康复和休息QEEG神经可塑性的影响:随机对照试验

Xiaoxue Zhai¹, Zexuan Hao², Xingui Wang²

¹Department of Rehabilitation Medicine, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua Medicine, Tsinghua University, Beijing, China.

Neurorehabilitation and neural repair

|February 12, 2026

概括

脑电脑接口 (BCI) 控制的脚机器人训练显著改善了中风后的下肢运动功能,并减少了性. 这种康复方法也促进了有益的神经可塑性变化,包括减少慢波活动和增强大脑连接.

科学领域:

神经科学是一个神经科学.
康复工程康复工程康复工程
临床神经学临床神经学

背景情况:

在中风后持续的脚损伤显著影响功能恢复.
脑计算机接口 (BCI) 控制的机器人系统对中风康复有希望,但它们的有效性和对神经可塑性的影响需要进一步研究.

研究的目的:

评估BCI控制的脚机器人训练对中风幸存者的运动恢复的影响.
在BCI机器人治疗后,使用定量脑电图 (qEEG) 评估神经质变化.

主要方法:

32名中风患者被随机分配到BCI机器人训练或常规脚机器人训练中2周.
用Fugl-Meyer评估-下肢 (FMA-LE),伯格平衡量级 (BBS),功能出行类别 (FAC),修改的阿什沃思量级 (MAS),活动运动范围 (AROM) 和肌肉力量来评估运动功能.
定量EEG (qEEG) 分析了三角形,三角形,α和β频段的功率,光谱比率,脑对称指数 (pdBSI) 和功能连接.

主要成果:

这两组在AROM,强度,FMA-LE,BBS和FAC方面都有所改善.
与对照组相比,BCI组在FMA-LE和减少小腿性 (MAS) 中表现出显著更大的改善.
在BCI组中,qEEG揭示了delta的降低和α功率的增加,减少了不对称性 (pdBSI-δ),以及功能连接的增强.

结论:

用BCI控制的脚机器人训练为中风后患者的运动功能和性减少提供了显著的好处.
在BCI训练中观察到的神经生理变化表明神经可塑性重组的增强,包括大脑活动的正常化和更好的连接性.

关键词:

大脑-计算机接口接口下肢康复治疗下肢康复治疗定量的脑电图 (EEG) 是一种量化脑电图.机器人机器人机器人机器人机器人机器人机器人一次性中风中风中风中风中风

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