耳鼻喉科-头手术中的放射学:一篇综述
Alexandra T Bourdillon1, Alexandria Yao2, Andrés M Bur3
1Department of Otolaryngology-Head and Neck Surgery, University of California, San Francisco.
JAMA otolaryngology-- head & neck surgery
|February 12, 2026
概括
放射学在耳鼻喉科有望改善诊断和治疗个性化. 标准化和验证是将这些成像生物标记工具集成到临床实践中的关键.
科学领域:
- 放射学利用可量化的成像生物标志物与他的病理学和临床结果相关联.
- 由于复杂的解剖学和多种病理学,这个领域在耳鼻喉学中提供了巨大的潜力.
背景情况:
- 放射学在耳鼻喉学中的应用主要集中在上呼吸道,喉,鼻通道和骨底部的瘤上.
- 目前的应用包括用于神秘特征的诊断分类器,复发和生存的预测器,以及治疗反应的预测器.
研究的目的:
- 在耳鼻喉科中建立放射学方法论框架.
- 确定阻碍临床翻译的常见局限性.
- 评估现场放射学现状和未来潜力.
主要方法:
- 这篇评论综合了现有的关于放射学在耳鼻喉学中的应用文献.
- 分析了方法框架,局限性和当前的进展.
- 审查的重点是诊断,预后和治疗预测应用.
主要成果:
- 放射学可以分类神秘的病理特征,并预测复发/生存,混合模型的表现优于单一模式的方法.
- 像dosiomics和δ-radiomics这样的技术在预测治疗反应和毒性方面具有潜力.
- 尽管取得了进展,但诸如可变协议,手动细分,小队列和缺乏验证等挑战阻碍了临床使用.
结论:
- 放射学与临床和病理学数据相结合,可以增强耳鼻喉科诊断,预后和治疗个性化.
- 成像协议的标准化,多机构验证和临床工作流程的整合对于采用至关重要.
- 精细的放射学应用可以简化工作流程并指导治疗规划.
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