肌肉炎的疼痛:患病率,评估,潜在的机制和管理方面的考虑
Stefanie Glaubitz1, Yvonne C Lee2, Didem Saygin3
1Department of Neurology, Neuromuscular Center, University Medical Center Göttingen, Germany.
Clinical and experimental rheumatology
|February 12, 2026
概括
异形性炎症性肌肉病变 (IIM) 经常引起疼痛,影响疾病活动和患者的功能. 本综述探讨了IIM患者的疼痛机制和管理策略.
科学领域:
- 类风湿病学 类风湿病学
- 神经学 神经学
- 疼痛医学 医学 疼痛医学
背景情况:
- 疼痛影响超过80%的患有异常性炎症性肌肉病变 (IIM) 的患者.
- 在IIM中疼痛的严重程度通常在10分之3到4之间.
- 肌肉炎相关的疼痛与疾病活动,炎症和中央敏感性有关.
研究的目的:
- 审查有关疼痛的当前知识和IIM的评估.
- 讨论肌肉炎相关疼痛的潜在机制.
- 探索 IIM 疼痛管理方面的考虑.
主要方法:
- 现有文献的叙述性审查.
- 在IIM中使用的疼痛评估工具的分析.
- 讨论导致疼痛的生物学和临床因素.
主要成果:
- 疼痛是IIM的一个显著和普遍的症状.
- 多种因素导致肌肉炎相关的疼痛,包括炎症和中央敏感化.
- 疼痛与较高的疾病活动,疲劳和较差的功能结果有关.
结论:
- 有效的疼痛评估和管理对于IIM患者至关重要.
- 了解疼痛机制可以指导治疗策略.
- 需要进一步研究多式联络性疼痛管理.
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