在神经化后监测神经再生和神经可塑性,使用针式电肌图.
Štěpánka Brušáková1, Ivan Humhej2, Jan Lodin2
1Department of Neurology, Masaryk Hospital Krajská Zdravotní a.s., Ústí nad Labem, Czech Republic.
概括
针电肌图 (EMG) 可以跟踪手臂损伤手术后的神经恢复. 在EMG上早期的再内尔化和同运动分辨率与更好的功能结果相关,这表明神经可塑性.
科学领域:
- 神经外科 神经外科
- 神经学 神经学
- 康复医学 康复医学 康复医学
背景情况:
- 臂损伤显著影响肩膀和肘部功能.
- 恢复包括轴突再生和中枢神经系统 (CNS) 神经可塑性.
- 目前用于评估神经可塑性的神经成像方法具有有限的临床实用性.
研究的目的:
- 评估针式电肌图 (EMG) 作为一种可重复的,低成本的方法,用于评估神经移植手术后的神经可塑性标记物.
- 为了将EMG发现的再内尔化和同运动与功能恢复相关联.
- 探索EMG在追踪从创伤性臂状结质损伤中恢复的临床实用性.
主要方法:
- 在21名患者的长度观察研究中,34名患者因臂损伤接受了近道神经移植.
- 连续EMG在≥36个月内进行,以评估自发活动,运动单元潜力和协同运动.
- 使用MRC尺度,度测量,马莱特尺度和DASH问卷进行评估的功能结果.
主要成果:
- 在58.8%的神经移植中取得了功能性成功 (MRC ≥3/5).
- 在53%的患者中观察到早期 (<6个月) 重内化,与肌肉强度增加相关 (Rs = 0.53,p < 0.01).
- 突触解脱发生在29%的患者中,与手术前的时间负相关 (Rs = -0.50,p = 0.005);突触解脱与更好的结果相关.
结论:
- 针EMG提供了系统和可访问的监测,重新内核和同步.
- 协同运动的解决可能意味着功能性皮质重组和改善患者康复.
- 这种基于EMG的方法值得进一步对临床应用进行前性验证.
相关概念视频
01:01Neuroplasticity
1.9K
Neuroplasticity reflects the brain's remarkable capacity to adapt and evolve, responding dynamically to learning, experiences, or injury by reorganizing its neural circuitry. This reorganization involves creating new neural connections and refining old ones through a series of biological processes that contribute to the brain's lifelong development and adaptability.
1.9K
01:23Holter Monitor: 24-Hour Monitoring
2.8K
Holter monitoring is a continuous electrocardiography (ECG) recording that tracks the heart's electrical activity over an extended period, generally 24 to 48 hours. This noninvasive diagnostic tool detects irregular heart rhythms that may not be captured during a standard ECG performed in a clinical setting.DeviceThe Holter monitor is a portable, small device connected to several electrodes on the patient's chest. These electrodes detect the heart's electrical signals and transmit them to the...
2.8K
02:05Self-Presentation: Self-Monitoring and Self-Handicapping
44.8K
People can go to great lengths to protect their self-image and present themselves in ways that they want others to see them. Sociologist Erving Goffman presented the idea that a person is like an actor on a stage. Calling his theory dramaturgy, Goffman believed that we use “impression management” to present ourselves to others as we hope to be perceived. Each situation is a new scene, and individuals perform different roles depending on who is present (Goffman, 1959). Think about...
44.8K
01:24Strategies of Self-Presentation III: Self-Monitoring
275
Self-monitoring is a central construct in understanding individual differences in self-presentation strategies across social contexts. It refers to how individuals observe, regulate, and control their expressive behavior and self-presentation following situational cues. Self-monitoring reflects a person's sensitivity to social appropriateness and willingness to adapt behavior to fit varying interpersonal demands.High vs. Low Self-Monitoring IndividualsIndividuals high in self-monitoring are...
275
01:29Therapeutic Drug Monitoring: Affecting Factors
252
Therapeutic Drug Monitoring (TDM) is the clinical practice of measuring specific drug levels in a patient's blood or body tissues to manage and optimize therapy. TDM is crucial for drugs with narrow therapeutic windows, like warfarin and phenytoin, where incorrect doses can lead to treatment failure or severe side effects. This monitoring ensures the dosage administered is within a safe and effective range. The factors affecting therapeutic drug monitoring include:Patient-Specific Factors:a.
252
01:25Errors occurring during blood pressure monitoring
1.5K
Blood pressure monitoring is a crucial clinical procedure in diagnosing and managing various cardiovascular conditions. Despite its significance, the accuracy of blood pressure measurements can be compromised by multiple factors, potentially leading to either falsely high or low readings. These inaccuracies are critical as they can significantly impact patient care. So, it is vital to understand these challenges deeply and adopt strategic approaches to minimize errors.
Several factors...
Several factors...
1.5K