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Updated: Feb 14, 2026

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突变的FGFR1是高风险神经母细胞瘤的致癌驱动因素和治疗点

Lisa Werr1, Jana Boland1, Josephine Petersen1

  • 1Department of Experimental Pediatric Oncology and Hematology, University of Cologne, Cologne, Germany.

The Journal of clinical investigation
|February 12, 2026
PubMed
概括

纤维细胞生长因子受体1 (FGFR1) 突变驱动高风险神经母细胞瘤. FGFR1 抑制剂对治疗这种侵袭性癌症充满希望,提供新的治疗途径.

关键词:
癌症 癌症 癌症 癌症细胞生物学 细胞生物学鼠标模型 鼠标模型在瘤学瘤学.

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