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Updated: Feb 14, 2026

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一种基于CRISPR的线粒体基因疗法工具,由工程指导RNAs衍生出来.

Ying Wang1, Xinwan Su1, Yu Chen1

  • 1College of Life Sciences, Zhejiang University, Hangzhou 310058, Zhejiang, China; Department of Respiratory and Critical Care Medicine, Center for RNA Medicine, the Fourth Affiliated Hospital of School of Medicine, and International School of Medicine, International Institutes of Medicine, Zhejiang University, Yiwu 322000, Zhejiang, China; Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, Hangzhou 310058, Zhejiang, China; Cancer Center, Zhejiang University, Hangzhou 310058, Zhejiang, China.

Cell reports
|February 12, 2026
PubMed
概括

研究人员开发了一种新的线粒体向序列 (RMTS),以将CRISPR基因编辑工具传递到线粒体中. 这一突破使线粒体DNA (mtDNA) 缺陷的有效纠正成为可能,为治疗线粒体遗传疾病提供了新的希望.

关键词:
CP:基因组学 在CP:基因组学这就是CRISPR-Cas系统.RNA识别动机是RNA的识别动机.这是线粒体DNA的DNA.线粒体疾病 线粒体疾病有机细胞关联RNA

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