一个双晶病毒基因组使用其3'端附近的紧型IV型IRES来表达一个跨膜蛋白质

Madeline E Sherlock1, Katherine E Segar2, Jeffrey S Kieft2

  • 1New York Structural Biology Center, New York, NY 10025, USA; Department of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.

Cell reports
|February 12, 2026
PubMed
概括

研究人员在巨型病毒E的3'未翻译区域 (UTR) 中发现了一个小的新型IV型内核糖核体入口点 (IRES).这种RNA元素能够实现独立于帽子的翻译,促进病毒蛋白的表达.

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