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Updated: Feb 14, 2026

Sequence-specific Labeling of Nucleic Acids and Proteins with Methyltransferases and Cofactor Analogues
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对于CRISPR激活的细菌辅因子

Zhipeng Wang1, Yujue Wang1, Quanjiang Ji1,2,3

  • 1School of Physical Science and Technology & State Key Laboratory of Advanced Medical Materials and Devices, ShanghaiTech University, Shanghai 201210, China.

Biochemistry
|February 12, 2026
PubMed
概括

细菌的硫素 (TrxA) 增强了Cas12p酶的DNA裂变活性. 这种由氧化还原敏感结合域介导的相互作用揭示了CRISPR-Cas系统是由辅助因素调节的.

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