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Updated: Feb 14, 2026

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替代拼接触发的mRNA衰变告知了神经发育障碍的拼接切换目标

Kaining Hu1, Runwei Yang1, Jiaming Qiu1

  • 1Department of Human Genetics, The Neuroscience Institute, University of Chicago, Chicago, United States of America.

The Journal of clinical investigation
|February 12, 2026
PubMed
概括

替代拼接触发的无意义介导的mRNA衰变 (AS-NMD) 调节数千个大脑基因,包括神经发育障碍的基因. 这项研究确定了针对自闭症等疾病的潜在治疗方法的新目标.

关键词:
发展发展发展 发展发展是一种病.神经发育 神经发育神经科学是一个神经科学.处理RNA处理RNA的过程

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